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How Gene Variations Affect Weight Management

You do everything you can to maintain a healthy body weight. You exercise. You eat healthy foods. You might even take supplements. But sometimes it's not just what you do that makes a difference; it could be what you're made of—literally.

FACT:

Two out of every three people in the United States is considered overweight.
(Source: Centers for Disease Control)

Genetics plays a crucial role in how efficiently we burn fat with exercise and how capable our bodies are to perform aerobic exercise. Variations in our genetic code can have both positive and negative effects on how our bodies react to the foods we eat and the workouts we put ourselves through. For example, one particular gene variation—ADRB2—could lead to increased fat accumulation in men and higher fat mass in women.

Most likely you don't know if you have these gene variations, which means you don't know what actions you can take to help maintain your optimal health. The Gene SNP DNA Analysis analyzes gene variants and your lifestyle choices to compile a personalized Health Action Plan that provides recommendations regarding lifestyle, diet, exercise and supplementation. The Gene SNP DNA Analysis can help you understand how these gene variations affect the choices you make—from diet to exercise to supplementation—so you can maintain optimal health.

FACT:

Three genes analyzed in the Gene SNP DNA Analysis - ADRB2, PPARgC1A and CRP - are associated with slower recovery after workouts.

What does Gene SNP test for related to weight management?

The Gene SNP DNA Analysis tests for seven (7) genes and their variations associated with weight management and exercise. While no amount of food or exercise will physically alter our genes, with proper nutritional supplementation and lifestyle changes, you can optimize the functioning of your gene variations to maintain optimal health.

ACE
muscle mass, use and retention
ADRB2, PPARgC1A & CRP
VO2 max
IL-6 & TNF-Alpha
Muscle recovery
ENOS
nitric oxide production

FACT:

Nearly two out of every five adults do not participate in leisure time physical activity.

Research about Weight Management

Association of the TNF-alpha -308G/A promoter polymorphism with insulin resistance in obesity. Read More

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Read More

Exercise-induced changes in insulin action are associated with ACE gene polymorphisms in older adults. Read More

FACT:

The ACE gene has two variations; one enhances your metabolism and endurance, while the other is associated with blood pressure. Which do you have?

The role PPARgamma in high-fat diet-induced obesity and insulin resistance. Read More

The TNF alpha/G-308A polymorphism influences insulin sensitivity in offspring of patients with coronary heart disease: the European Atherosclerosis Research Study II. Read More

Paolisso, G., et al, ACE gene polymorphism and insulin action in older subjects and healthy centenarians. J Am Geriatr Soc 49, 610-614 (2001). Read More

The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study. Read More

Peroxisome proliferator-activated receptor-gammaPro12Ala polymorphism and the association with blood pressure in type 2 diabetes: skaraborg hypertension and diabetes project. Read More

ACE gene polymorphism and insulin action in older subjects and healthy centenarians. Read More

Relationship between angiotensin-converting enzyme gene polymorphism and insulin resistance in never-treated hypertensive patients. Read More

FACT:

Joints hurt after exercising? It may be genetic, as the IL-6 & TNF-Alpha gene variants have been associated with comfort and health.

Weight Management News

TheHeart.org - Dieting by DNA? Popular diets work best by genotype, research shows Read More

USA Today - Middle-aged dieters hit a brick wall after 10 pounds or so Read More

WRAL.com - DNA tests can help dieters Read More

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